The Effect of Respiratory Muscle Warm-up on Pulmonary Diffusion Capacity in Athletes

Emre Karaduman

Status: Not yet enrolling

Conditions: Athlete; Healty Male Volunteers

Treatments: Other: Inspiratory muscle warm-up; Other: Inspiratory muscle warm-up placebo (IMW %15); Other: General warm-up (Control)

Study type: Interventional

Funder types: Other

Identifiers

NCT06736236

PYO.YDS.1901.22.002

Details and patient eligibility

About

Several studies suggest that inspiratory muscle warm-up (IMW) could potentially affect exercise performance; however, its mechanistic basis is still unclear. The aim of this study was to examine the effect of IMW on lung diffusing capacity for carbon monoxide, cardiorespiratory, perceptual and performance outcomes in elite athletes from different disciplines.

The aim of this study is to evaluate the effects of IMW on diffusion capacity for carbon monoxide, cardiorespiratory, perceptual and performance outcomes during high-intensity exercise in elite athletes from different disciplines. The study will be conducted using a randomized, placebo-controlled, double-blind and crossover study experimental design involving 35 athletes from various sports disciplines, including endurance, strength, skill-based, and mixed disciplines.

Participants will attend the laboratory on four separate occasions. During the first visit, they will be informed about the study and familiarized with the application and measurement procedures. In the second visit, a general warm-up will be performed. During the third and fourth visits, IMW (IMW40% or IMW placebo) protocols will be applied in addition to the general warm-up. Measurements of DLCO, pulmonary function tests, respiratory muscle strength, and gas analysis during maximal aerobic exercise will be collected both before and after the warm-up protocols.

Full description

A. STUDY DESING This study will employ a placebo-controlled, randomized, crossover, and double-blind research design to evaluate the effects of three warm-up conditions: Control, Placebo 15%, and IMW 40%. Athletes will be randomly assigned to the conditions using a crossover approach, ensuring that all participants will experience each protocol on separate days.

The warm-up protocols will include:

General Warm-up (Control): A standard warm-up without resistance. IMW 40%: A general warm-up combined with respiratory muscle exercise at 40% resistance.

Placebo 15%: A general warm-up combined with placebo respiratory muscle exercise at 15% resistance.

Blinding will be maintained for both participants and researchers. Participants will be informed that the study aims to investigate various warm-up types, while the true purpose will remain concealed. This design will ensure reliability and minimize bias in the data to be collected.

Enrollment: 35 estimated patients

Sex: Male

Ages: 18 to 24 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age between 18-24 years.
• A training history of at least six years.
• Regular training frequency of at least four sessions per week.

Exclusion criteria

• History of smoking.
• History of physical disability or acute respiratory or cardiovascular disease within the past three months.
• Diagnosis of SARS-CoV-2 within the past three months.
• Pulmonary function measurements outside the normal clinical range (≤ 80%).

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Double Blind

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35 participants in 3 patient groups, including a placebo group

Control

Other group

Description:

Participants only performed a general warm-up exercise.

Treatment:

Other: General warm-up (Control)

IMW %15 (Placebo)

Placebo Comparator group

Description:

In addition to the general warm-up, the participants performed IMW at 15% resistance intensity.

Treatment:

Other: Inspiratory muscle warm-up placebo (IMW %15)

IWM %40 (Experimental)

Experimental group

Description:

In addition to the general warm-up, participants performed IMW at 40% resistance intensity.

Treatment:

Other: Inspiratory muscle warm-up