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The Effect of Salpingectomy Operation on Ovarian Reserve

D

Dokuz Eylül University (DEU)

Status

Completed

Conditions

Ovarian Insufficiency

Treatments

Procedure: bilateral salpingectomy, ovarian arter doppler ultrasonography

Study type

Observational

Funder types

Other

Identifiers

NCT06903650
SOORAMHODU

Details and patient eligibility

About

This study aimed to evaluate the effect of salpingectomy operation on ovarian reserve. Ovarian reserve was evaluated by measuring anti-mullerian hormone levels from serum samples taken from the patients before the operation and 6 weeks after the operation. Ovarian doppler flow were evaluated by measuring the ovarian artery pulsatility index with transvaginal ultrasonography preoperatively, postoperative days 2 and postoperative weeks 6 . In our study, it was determined that ovarian functions may be negatively affected in the acute period after salpingectomy operation.

Enrollment

31 patients

Sex

Female

Ages

37 to 45 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  1. Women between the ages of 37-45 with continuing menstrual cycles (37 and 45 included)
  2. Patients who will undergo uterine surgery for benign reasons or who will undergo salpingectomy only due to hydrosalpinx, ectopic pregnancy, tubo-ovarian abscess
  3. Patients who have not had ovarian surgery before
  4. Those without menopause and premature ovarian failure
  5. Patients who accept the study

Exclusion criteria

  1. Age younger than 37 or older than 45
  2. Those who want to withdraw from the study
  3. Those who do not come for follow-up examination
  4. Use of drugs that affect ovarian reserve
  5. Any surgical procedure performed on the ovaries during the operation
  6. No menstrual bleeding in the last year
  7. Patients who received radiotherapy and hormonal therapy within 3 months before surgery

Trial design

31 participants in 3 patient groups

perioperative ovarian arter pulsatility index(PI)(right and left), perioperative AMH levels
Treatment:
Procedure: bilateral salpingectomy, ovarian arter doppler ultrasonography
postoperative days 2 ovarian arter pulsatility index (PI) (right and left)
Treatment:
Procedure: bilateral salpingectomy, ovarian arter doppler ultrasonography
postop. weeks 6 ovarian arter pulsatility index(PI)(right and left), postop. weeks 6 AMH levels
Treatment:
Procedure: bilateral salpingectomy, ovarian arter doppler ultrasonography

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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