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The Effect of Segmental Re-examination of Colon for Adenoma Detection in Colonoscopy

T

The Catholic University of Korea

Status

Completed

Conditions

Adenoma

Treatments

Other: segmental reexamination

Study type

Interventional

Funder types

Other

Identifiers

NCT03268200
reexamination

Details and patient eligibility

About

The aim of this study was to determine whether segmental re-examination of the each segment (right colon, mid-colon, and left colon) could increase the proximal adenoma detection rate (ADR) and to evaluate the time-effectiveness of this approach.

Full description

The investigators prospectively recruited patients (aged ≥45 and ≤75 years) who were scheduled to undergo colonoscopy at our center. Patients were excluded if they had advanced colonic cancer, prior resection of the proximal colon, inflammatory bowel disease, or polyposis syndrome, or were unable to provide informed consent. In addition, if the quality of bowel preparation was unsatisfactory (Boston Bowel Preparation Scale [BBPS] score <2 in any segment of the colon), or if the cecum could not be intubated during the colonoscopy, patients were excluded.

A randomization list was generated with the randomization algorithm of random sorting, using Excel program. Included patients were randomly assigned to one of the two groups: segmental re-examination group, in which the each segment (right colon, mid-colon, and left colon) was examined twice segmentally; or control group, in which the withdrawal time in the each segment was about 2 minutes.

Enrollment

450 patients

Sex

All

Ages

45 to 75 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Patients (aged ≥45 and ≤75 years) who were scheduled to un- dergo colonoscopy

Exclusion criteria

  • Patients who had advanced colonic cancer, prior resection of the proximal colon, inflammatory bowel disease, or polyposis syndrome, or were unable to provide informed consent.
  • If the quality of bowel preparation was unsatisfactory (Boston Bowel Preparation Scale [BBPS] score <2 in any segment of the colon), or if the cecum could not be intubated during the colonoscopy, patients were excluded.

Trial design

Primary purpose

Diagnostic

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Single Blind

450 participants in 2 patient groups

Case group
Experimental group
Description:
Each segment of colon (right colon, mid-colon, and left colon) was examined twice
Treatment:
Other: segmental reexamination
Control group
No Intervention group
Description:
Withdrawal time in the each segment of colon (right colon, mid-colon, and left colon) was about 2 minutes.

Trial contacts and locations

1

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Central trial contact

Jeong-Seon Ji, PhD

Data sourced from clinicaltrials.gov

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