The Effect of Sildenafil on Sleep-Disordered Breathing in Obese Patients With Sexual Dysfunction

Shamir Medical Center (Assaf-Harofeh)

Status: Unknown

Conditions: Sildenafil; Sexual Dysfunction; Obesity; Sleep Apnea

Study type: Observational

Funder types: Other

Identifiers

NCT00893191

39/09

Details and patient eligibility

About

Sildenafil has been shown to aggravate sleep-disordered breathing in patients with severe obstructive sleep apnea. The aim of the present study is to examine the frequency of sleep-disordered breathing in obese patients who are candidates for treatment with sildenafil for sexual dysfunction. In addition we wish to assess the effect of sildenafil on sleep-disordered breathing.

Enrollment: 50 estimated patients

Sex: Male

Ages: 40 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age - 40-65 years
• BMI equal to or over 30

Exclusion criteria

• A known cardiorespiratory, liver or kidney disease
• Treatment with nitrates or alfa blockers
• Performed polysomnography in the past

Trial design

50 participants in 2 patient groups

Sildenafil

Description:

Treated with 50 mg of Sildenafil at night

Placebo

Description:

Treated with placebo at night