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The Effect of Soluble Fiber Dextrin on Subjective and Physiological Markers of Appetite

I

Iowa State University

Status

Completed

Conditions

Appetitive Behavior

Treatments

Other: Soluble Fiber Dextrin

Study type

Interventional

Funder types

Other

Identifiers

Details and patient eligibility

About

This study examines the effect of soluble fiber dextrin on food intake, appetite, and physiological markers of appetite. Adults aged 18-45 years with a BMI were recruited for this study. Participants were given two doses of SFD in the morning and appetite, food intake and physiological markers of appetite were measured over 10 years.

Full description

Overweight and obesity are leading health problems. The study investigates the effect of a food ingredient from two different sources at two different doses on food intake and appetite markers over a 10 hour period. All participants reported to the laboratory first thing in the morning and remained in the laboratory until after their evening meal. A fixed breakfast was served but the participants were free to eat as much as they liked at lunch and dinner. Blood was taken at regular intervals during the day and assayed for glucose and several hormones related to appetite. Subjective measures of appetite were also collected over the 10 hour test session.

Enrollment

50 patients

Sex

All

Ages

18 to 45 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

BMI 19.9 - 29.9 Aged 18-45 Find the study foods to be palatable

Exclusion criteria

Weight change > 3kg in the past three months Do not regularly consume snacks Presence or history of GI disorders Restrained eater Used medication that influences appetite

Trial design

Primary purpose

Basic Science

Allocation

Randomized

Interventional model

Crossover Assignment

Masking

Double Blind

50 participants in 5 patient groups, including a placebo group

SFD Tapioca 20g
Experimental group
Description:
20g soluble fiber dextrin derived from tapioca
Treatment:
Other: Soluble Fiber Dextrin
SFD Tapioca 40g
Experimental group
Description:
40g soluble fiber dextrin derived from tapioca
Treatment:
Other: Soluble Fiber Dextrin
SFD corn 20g
Experimental group
Description:
40g soluble fiber dextrin derived from corn
Treatment:
Other: Soluble Fiber Dextrin
SFD corn 40g
Experimental group
Treatment:
Other: Soluble Fiber Dextrin
Control
Placebo Comparator group
Description:
Maltodextrin
Treatment:
Other: Soluble Fiber Dextrin

Trial contacts and locations

0

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Data sourced from clinicaltrials.gov

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