The Effect of Spermatic Vein Embolization on Prostatic Hypertrophy

Maaynei Hayesha Medical Center

Status: Completed

Conditions: Varicocele

Treatments: Procedure: Sclerotherapy

Study type: Interventional

Funder types: Other

Identifiers

NCT00639899

RVS-001-IL

Details and patient eligibility

About

In varicocele the venous pressure in the prostatic bed is increased .This may result in raised hydrostatic pressure which in turn may stimulate prostatic hypertrophy.

Restoring normal venous drainage is expected to lower hydrostatic pressure followed by inhibition of prostatic growth and possibly leading regression in prostatic dimensions.

Full description

35 male patients, aged 45 years or older, with documented benign prostatic hypertrophy (BPH)and varicocele as visualized by ultrasound and/or termography examination will be enrolled.

Each patient will undergo a full urologic examination to exclude possible malignancy as well as a thorough medical examination to establish eligibility for treatment.

In all selected patients the varicocele will be obliterated by means of embolization of the spermatic veins.

The patients will be followed every three months by abdominal ultrasound as well as by serial PSA for a period of 6-12 months.

Enrollment: 35 patients

Sex: Male

Ages: 45 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Male
• Age > 45 < 80 years
• BPH
• Bilateral varicocele.

Exclusion criteria

• Coagulation disturbance
• CHF
• Malignancy
• Renal failure.

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)