The Effect of Spinal Anesthesia on Hemodynamics

Ankara City Hospital

Status: Completed

Conditions: Anesthesia, Spinal

Treatments: Other: 7.5 mg hyperbaric bupivacaine; Other: 5 mg hyperbaric bupivacaine

Study type: Interventional

Funder types: Other

Identifiers

NCT05896631

geriatrics

Details and patient eligibility

About

In this study, it was planned to provide more stable hemodynamics in geriatric patients with low-dose spinal anesthesia. We will compare 7.5mg hyperbaric bupivacaine with 5mg hyperbaric bupivacaine.

The researchers hypothesized that low-dose bupivacaine would provide adequate anesthesia, less hypotension, and faster recovery.

Full description

Hypothesis It is hypothesized that low-dose bupivacaine can provide adequate anesthesia, less hypotension, and faster recovery.

patient population Patients over 65 years of age who will undergo spinal anesthesia due to hip fracture.

Hemodynamic data(Blood pressure-mmHg, heart rate-beats per minute) of patients, bromage scores, perfusion index (PI) values, discharge time, pain with NRS (numerical rating scale), patient satisfaction will be evaluated ( Numeric output from 1-10).

Hemodynamic variables will be recorded every 2 minutes in the first 20 minutes after spinal anesthesia. hemodynamic variables will be recorded 30 minutes after spinal anesthesia and at the end of the operation.

The perfusion index is the ratio of the blood volume to the pulsatile to non-pulsatile fraction. An increase in the pulsatile fraction that occurs during vasodilation corresponds to a higher PI. Therefore, patients with a higher PI have a higher risk of post-spinal hypotension.

Enrollment: 80 patients

Sex: All

Ages: 65+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• ASA(American Society of Anesthesiologists) I-II-III patients
• BMI( body mass index) in the range of 18-40
• over 65 years old hip fracture

Exclusion criteria

• Refusal to participate in the study
• Left ventricular ejection fraction below 40%
• cardiac arrhythmia
• Patients with peripheral vascular disease
• Failure of spinal anesthesia

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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80 participants in 2 patient groups

7.5 mg hyperbaric bupivacaine

Active Comparator group

Description:

Patients undergoing spinal anesthesia in the lateral decubitus position with 7.5 mg of hyperbaric bupivacaine will be included.

Treatment:

Other: 7.5 mg hyperbaric bupivacaine

5 mg hyperbaric bupivacaine

Active Comparator group

Description:

Patients undergoing spinal anesthesia in the lateral decubitus position with 5 mg of hyperbaric bupivacaine will be included.

Treatment:

Other: 5 mg hyperbaric bupivacaine