the Effect of Spray on Propofol Injection Pain

The Catholic University of Korea

Status and phase: Completed; Phase 4

Conditions: Pain

Treatments: Drug: lidocaine; Drug: ethyl chloride spray; Drug: placebo

Study type: Interventional

Funder types: Other

Identifiers

NCT02770690

CMC 2016-1

Details and patient eligibility

About

While propofol is widely used an anesthetic induction medication, it causes the mild to moderate pain. Investigators will investigate the effect of ethyl chloride spray on propofol injection pain.

Enrollment: 90 patients

Sex: Female

Ages: 20 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• the female patients undergoing hysteroscopy

Exclusion criteria

• the patients who are pregnant, have Raynaud's syndrome, or receive the pain killer

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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90 participants in 3 patient groups, including a placebo group

spray

Experimental group

Description:

apply the ethyl chloride spray before propofol injection

Treatment:

Drug: ethyl chloride spray

lidocaine

Active Comparator group

Description:

apply the lidocaine 0.5 mg/kg under the touniquette state before propofol injection

Treatment:

Drug: lidocaine

placebo

Placebo Comparator group

Description:

apply the saline before propofol injection

Treatment:

Drug: placebo