The Effect of Steep Trendelenburg Position on Neurocognitive Functions in Robotic Radical Prostatectomy Cases

Ankara City Hospital

Status: Not yet enrolling

Conditions: Robotic Assisted Laparoscopic Radical Prostatectomy; Neurocognitive Disorder; Near Infrared Spectroscopy

Treatments: Diagnostic Test: Montreal Cognitive Assessment

Study type: Observational

Funder types: Other

Identifiers

NCT06869304

TABED2-24-570

Details and patient eligibility

About

The aim of this study is to evaluate the effects of the steep Trendelenburg position in robotic prostatectomy cases, where anesthesia depth is monitored using BIS and cerebral perfusion is tracked with NIRS, and to determine the incidence of neurocognitive dysfunction using the MoCA test in the postoperative period.

Steep Trendelenburg position and CO₂ pneumoperitoneum during robotic radical prostatectomy lead to significant changes in intracranial pressure and cerebral oxygenation, which may contribute to postoperative neurocognitive dysfunction (POCD). Monitoring anesthesia depth with Bispectral Index (BIS) and cerebral perfusion with Near-Infrared Spectroscopy (NIRS) may help detect early neurocognitive changes, and MoCA test assessments will reveal a measurable decline in cognitive function postoperatively.

Enrollment: 56 estimated patients

Sex: Male

Ages: 65 to 100 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age ≥ 65 years
• ASA II-III risk score
• Patients scheduled for robotic radical prostatectomy
• Patients who voluntarily agree to participate

Exclusion criteria

• Age < 65 years
• History of neurological or psychiatric disorders
• Inability to undergo robotic surgery
• Conversion to open prostatectomy during surgery
• Patients who do not consent to participate