The Effect of Suturing Material on Scar Healing

Bezmialem Vakif University

Status: Completed

Conditions: Cesarean Section Complications; Wound Heal; Suture Related Complication; Cesarean Wound Disruption

Treatments: Other: Multifilament suture; Other: Monofilament suture

Study type: Interventional

Funder types: Other

Identifiers

NCT03968783

Cesarean suture study

Details and patient eligibility

About

We want to compare the effects of 2 suture materials (monofilament and multifilament) on healing of the uterine scar after a cesarean delivery.

Full description

Cesarean section (CS) is the most common type of obstetric surgery. When medically justified, CS can effectively prevent maternal and perinatal mortality and morbidity however, there are many short and long-term complications of CS. One of the most common complications is the CS scar defect. CS scar defects can develop after transverse incision of the lower uterine segment, which may result in prolonged postmenstrual bleeding, spotting, pelvic pain, and infertility. Suture material is an essential part of any major surgery, serving to hold opposing tissues together and accelerate the healing process, resulting in decreased scarring of the affected areas. We sought to evaluate the effects of different synthetic absorbable suture materials on cesarean scar defect formation.

Enrollment: 95 patients

Sex: Female

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• singleton pregnancy at term >37 weeks of gestational age

Exclusion criteria

• history of previous cesarean section
• history of previous uterine surgery
• multiple gestation, placenta previa, polyhydramnious, fetal macrosomia
• uterine atony history
• gestational diabetes mellitus, gestational hypertension, preeclampsia, current or previous history of heart disease, liver, renal disorders or known coagulopath
• active labor (with regular uterine contractions and cervical dilatation >4 cm

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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95 participants in 2 patient groups

Monofilament suture

Experimental group

Description:

continuous double-layer unlocked suturing with 1.0 monofilament synthetic absorbable suture

Treatment:

Other: Monofilament suture

Multifilament suture

Active Comparator group

Description:

continuous double-layer unlocked suturing with 1.0 multifilament synthetic absorbable suture

Treatment:

Other: Multifilament suture