The Effect of TaiChi on Ischemic Burden of Patients With Coronary Heart Disease Complicated With Renal Insufficiency

Capital Medical University

Status: Not yet enrolling

Conditions: Renal Insufficiency; Coronary Heart Disease (CHD)

Treatments: Behavioral: Tai Chi Intervention Group

Study type: Interventional

Funder types: Other

Identifiers

NCT05178602

TaiChi trial

Details and patient eligibility

About

This study focuses on patients with incomplete revascularization combined with renal insufficiency. And since heart and kidney are two organs influence each other, the study take the mechanism of heart and kidney comorbidity and the risk factors of the two organs.As one of the traditional Chinese sports, Tai Chi is an aerobic exercise combineing movements with static postures, which can significantly improve the aerobic endurance of patients with coronary heart disease. In this study, a parallel, randomized controlled study method is used to quantitatively evaluate the myocardial ischemia condition by myocardial perfusion imaging indicators. This study aims to figure out whether the cardiac rehabilitation training program based on Tai Chi has a positive effect on the patients' myocardial ischemic.

Enrollment: 142 estimated patients

Sex: All

Ages: 30 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. 30-75 years old, all genders;
2. At least two main vessels or their main branch vessels have obvious stenosis (≥50%) according to the coronary angiography;
3. Received stent implantation and incomplete revascularization (incomplete revascularization: at least one vessel whose a diameter> 2.0 mm and at least one lesion with a stenosis> 50%, after PCI);
4. eGFR<60ml/min·1.73m2;
5. Willing to be treated and followed-up during the specified time of the study;
6. Signed the informed consent approved by the Ethics Committee

Exclusion criteria

1. Patients with high-risks according to the exercise rehabilitation risks of patients with heart disease by AACVPR;
2. Severe cardiac insufficiency or cardiogenic shock;
3. Combined with severe ventricular arrhythmia, ICD is required;
4. Combined with severe pulmonary hypertension, chronic obstructive pulmonary disease, severe infectious disease, blood system disease, malignant tumor, severe liver damage, etc.;
5. Nervous, mental and motor system diseases;
6. Unwilling to be followed-up.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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142 participants in 2 patient groups

The experimental group

Experimental group

Description:

Routine treatment, and tai Chi exercise,5 times a week

Treatment:

Behavioral: Tai Chi Intervention Group

The control group

No Intervention group

Description:

Routine treatment, and cardiac rehabilitation is not mandatory