The Effect of Tear Supplements on Contact Lens Comfort

University of the Incarnate Word

Status: Completed

Conditions: Meibomian Gland Dysfunction; Dry Eye Syndromes

Treatments: Other: Systane Contacts eye drops; Other: saline; Other: Systane Balance eye drops

Study type: Interventional

Funder types: Other

Identifiers

NCT02956083

14-04-013

Details and patient eligibility

About

The primary goal of this investigation is to determine if lipid based artificial tear supplementation has an impact on contact lens discomfort (CLD).

Full description

Contact lens discomfort (CLD) is the most common cause of discontinuing contact lens wear. Despite years of research and innovations in technology, CLD remains highly prevalent, and thus it is a major concern for patients and practitioners. Studies suggest that meibomian gland dysfunction (MGD) is a cause of CLD. Several lipid-based artificial tears have recently been designed to address dry eye associated with MGD. In this study, the investigators examine if the benefits of lipid based artificial tears extend to improving contact lens comfort. Studies have demonstrated some usefulness of non-lipid based tear supplements in the management of contact lens discomfort. However, the relief was moderate and short-term. To date, no study has examined the impact of lipid based artificial tears on contact lens discomfort. In this study, the investigators will address this gap in knowledge.

Enrollment: 30 patients

Sex: All

Ages: 21+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients complaining of contact lens associated discomfort

Exclusion criteria

• Patients who do not have contact lens discomfort; patients who have active inflammation or infection of the anterior segment of the eyes.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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30 participants in 3 patient groups, including a placebo group

Lipid based artificial tears

Active Comparator group

Description:

Patients use lipid based artificial tears

Treatment:

Other: Systane Balance eye drops

Non-lipid based artificial tears

Active Comparator group

Description:

patients use non-lipid based artificial tears

Treatment:

Other: Systane Contacts eye drops

Saline

Placebo Comparator group

Description:

patients use saline

Treatment:

Other: saline