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The Effect of the 3/7 vs 3X9 Method in Resistance Training on Metabolic Stress in Cardiac Rehabilitation

U

Université Libre de Bruxelles

Status

Completed

Conditions

Coronary Artery Disease
Resistance Training
Heart Failure

Treatments

Other: Cardiac rehabilitation with 3/7 method
Other: Cardiac rehabilitation with 3X9 method

Study type

Interventional

Funder types

Other

Identifiers

NCT05391620
2020276

Details and patient eligibility

About

The study proposes to measure the effect of resitance training (RT) (3/7 method) on biological markers of muscle hypertrophy in a cardiac population.

3/7 method consisting of five sets of an increasing number of repetitions (3 to 7) during successive sets and brief inter-set intervals (15 s). This method is compare to 3X9 method, 3 series of 9 repetitions with inter-set (1min).The training exercise consisted of contraction on machine (leg press, triceps press, leg curl, traction, leg extension) with load of ~ 70% of one repetition maximal (1RM).

Before these trainings all subject perform HIIT on bicycles (2 min high intensity (80% Wmax) and 2 min low intensity (50% Wmax) during 30 minutes.

The investigators collect blood sample before exercice, after HIIT and after RT.

It is randomized cross-over study.

Full description

The subjects come on two different days minimum 2 days and maximum 10 days between the two tests. They were instructed to avoid exercise the day before they participated in the study.

The investigators collect blood 2 minutes after endurance training (HIIT) and 2 min after RT training.

Enrollment

25 patients

Sex

Male

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Clinical Coronary artery diseases
  • Heart failure with reduced ejection fraction

Exclusion criteria

  • angina
  • acutely decompensated heart failure
  • electrocardiographic evidence of ischemia
  • significant valvular disease
  • orthopedic/neurologic disorders that limited exercise

Trial design

Primary purpose

Other

Allocation

Randomized

Interventional model

Crossover Assignment

Masking

Double Blind

25 participants in 2 patient groups

CAD group
Experimental group
Description:
Coronary artery diseases
Treatment:
Other: Cardiac rehabilitation with 3X9 method
Other: Cardiac rehabilitation with 3/7 method
HFrEF group
Experimental group
Description:
Heart Failure with reduced Ejection Fraction
Treatment:
Other: Cardiac rehabilitation with 3X9 method
Other: Cardiac rehabilitation with 3/7 method

Trial contacts and locations

1

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Central trial contact

Alexis Gillet, Pt, Msc; Philippe van de borne, Professor

Data sourced from clinicaltrials.gov

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