The Effect of Topical Sunscreen Plus Antioxidant Against the Visible Light Biological Effects

Henry Ford Health

Status

Completed

Conditions

Pigmentation

Treatments

Other: Control

Other: Topical Product A

Other: Topical Product C

Other: Topical Product B

Study type

Interventional

Funder types

Other

Industry

Identifiers

NCT03065582

IRB # 9695

Details and patient eligibility

About

Visible light is known to induce pigmentation in darker skin types. The investigators aim to study the effects of visible light on the skin after topical application of sunscreen plus antioxidant.

Enrollment

32 patients

Sex

All

Ages

18+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Patient age 18 and older
Patients Fitzpatrick skin phototype IV-VI
Patient able to understand requirements of the study and risks involved
Patient able to sign a consent form

Exclusion criteria

A recent history of vitiligo, melasma, and other disorders of pigmentation with the exception of post inflammatory hyperpigmentation
A known history of photodermatoses
A known history of melanoma or non-melanoma skin cancers
Those planning on going to the tanning parlors
Using any of the photosensitizing medication within the visible light range or additional medications at the discretion of the investigator (examples include (but not limited to) thiazide diuretics, regular use of NSAIDs, hydroxychloroquine, or voriconazole)
A woman who is lactating, pregnant, or planning to become pregnant
Patient planning on exposing the irradiated or control areas to the sun
known allergy to anesthetics (lidocaine or epinephrine)