The Effect of Training on Endothelial Function, Progression of Disease,Inflammation, Heart Rate Variability and Mental Health After Percutaneous Coronary Intervention (EFECTOR)

Helse Stavanger HF

Status and phase: Completed; Phase 4

Conditions: Coronary Artery Disease

Treatments: Behavioral: exercise training

Study type: Interventional

Funder types: Other

Identifiers

NCT00469950

3.2005.1437

Details and patient eligibility

About

The Efector study is an open, randomized and controlled trial assessing the effect of regular exercise training on endothelial function, inflammatory markers, progression of disease, heart rate variability and mental health in patients who have been successfully treated with percutaneous coronary intervention and stent implantation for angina pectoris.

Full description

Pas er randomized to a 6 months training group or none training. At baseline and at 6 months patients are examined with blood tests to measure serum concentrations of inflammatory markers, a test for endothelial function, heart rate variability and a coronary angiogram. Further patients are asked to answer questionnaires concerning mental health (SF36, HADS).

Enrollment: 40 estimated patients

Sex: All

Ages: 18 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Successful PCI with stent implantation,
• Able to participate in the training program,
• No planned further revascularisation

Exclusion criteria

• CAGB,
• Inflammatory diseases other than CAD,
• Heart failure,
• Severe kidney failure,
• Inability to participate in the training program

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)