The Effect of Transcranial Direct Stimulation on Cognitive Functions of Healthy Adults

Medipol University

Status: Completed

Conditions: Healthy; Cognitive Symptom

Treatments: Other: Transcranial Direct Current Stimulation

Study type: Interventional

Funder types: Other

Identifiers

NCT04873804

tDCS on DLPFC and PPC

Details and patient eligibility

About

Background: Transcranial direct current stimulation(tDCS) has been used to improve cognitive functions in healthy young adults.

Purpose: To investigate the effect of TDCS application on different cortex regions on cognitive function.

Methods: Sixty individuals aged 18-30 were included in the study. The participants were randomly divided into the left dorsolateral prefrontal cortex (Left DLPFC Group)(n=20), the right posterior parietal cortex (Right PPC Group)(n=20), and the sham group (Sham Group)(n=20). tDCS was applied for 20 minutes on weekdays for 2 weeks. The participants were evaluated in terms of cognitive functions with Neuropsychometric Test Battery before and after treatment.

Enrollment: 57 patients

Sex: All

Ages: 18 to 30 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• being 18-30 years old

Exclusion criteria

• alcohol and substance addiction
• previous mental illness
• having mental and cognitive problems
• a history of head trauma
• having cardiovascular disease.

Trial design

Primary purpose: Diagnostic

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

---

57 participants in 3 patient groups

LEFT DLPFC

Active Comparator group

Description:

The anode electrode of tDCS was applied to the left DLPFC and the cathode electrode was connected to the contralateral shoulder.

Treatment:

Other: Transcranial Direct Current Stimulation

RİGHT PPC

Active Comparator group

Description:

The anode electrode of tDCS was applied to the right PPC and the cathode electrode was connected to the contralateral shoulder.

Treatment:

Other: Transcranial Direct Current Stimulation

Sham

Sham Comparator group

Description:

Placebo was applied by placing the electrodes in the right PPC and left DLPFC without applying current.

Treatment:

Other: Transcranial Direct Current Stimulation