The Effect of Ultrasound-guided Erector Spinae Block on Postoperative in Patients Undergoing Nephrectomy.

Namik Kemal University

Status: Completed

Conditions: Nephrectomy

Treatments: Procedure: erector spinae block (ESP)

Study type: Interventional

Funder types: Other

Identifiers

NCT04703634

Interventional (Other Identifier)

Details and patient eligibility

About

The main purpose of this study is to evaluate the postoperative effect of erector spinae block in patients undergoing nephrectomy that causes both visceral and somatic pain.

Full description

After being informed and potential risks about the study, all patients have given written consent will undergo 24 hours screening for the analgesic effect of erector spinae block after nephrectomy. Patients meeting the criteria were randomly selected in double-blind manner 1:1 ratio to erector spiane block or not.

Enrollment: 30 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. To undergo partial or total nephrectomy surgery
2. To be in ASA I-II classification
3. To be between the ages of 18-65.
4. Not having problems that prevent erector spinae block application such as local anesthetic drug allergy, infection at the injection site, and structural anomaly.
5. Being in good mental and psychological health
6. To accept to participate in the study.

Exclusion criteria

1. Being in ASA III or IV class with a high risk of anesthesia
2. Being outside the age range of 18-65
3. Having problems such as local anesthetic drug allergy, infection at the injection site, and structural anomaly prevents block application.
4. Not being mentally and psychologically healthy
5. Those who are allergic to the active substance, patients using antiepileptic drugs
6. Those with severe hepatic and renal failure
7. Those who have long-term use of nonsteroidal anti-inflammatory and opioid analgesic,
8. Those with diabetes and other neuropathic diseases
9. Patients who cannot use patient-controlled analgesia (PCA) device

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Single Group Assignment

Masking: Double Blind

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30 participants in 2 patient groups, including a placebo group

erector spinae group

Experimental group

Description:

All blocks will be done under general anesthesia. Using a 6-10 MHz linear ultrasound (Esaote my-lab 6, Italy). With the ultrasonography device of our clinic, the side of the nephrectomy surgery will be performed with the position of the nephrectomy, and the position (lateral decubitus) is given to the patient. The thoracic 10th vertebra will be found under ultrasound guidance. After the T12 transverse protrusion is seen by sliding 3 cm laterally from the midline, 30 ml of 0.25% Bupivacaine will be injected under the erector spinae muscle above it.

Treatment:

Procedure: erector spinae block (ESP)

placebo group

Placebo Comparator group

Description:

No block transaction will be applied to this group. Only postoperative analgesia methods will be used for this group as specified in the protocol.

Treatment:

Procedure: erector spinae block (ESP)