The Effect of UVB Phototherapy With Microneedling and Circled Needing in Vitiligo Patients

Shin Kong Wu Ho-Su Memorial Hospital

Status: Completed

Conditions: Brief Description of Focus of Study Instead

Treatments: Device: Surrounding needling+ phototherapy; Device: phototherapy

Study type: Interventional

Funder types: Other

Identifiers

NCT03718962

20180205R

Details and patient eligibility

About

Vitiligo is a relatively common acquired disorder of pigmentation characterized by the development of well-defined white macules on the skin. Biopsies of lesional skin reveal a loss of epidermal melanocytes. Lesions may occur in a localized or generalized distribution and may coalesce into large, depigmented areas. Given the contrast between the white areas and normal skin, the disease is most disfiguring in darker skin types and has a profound impact on the quality of life of both children and adults . Patients with vitiligo often experience stigmatization, social isolation, and low self-esteem. The therapys include topical steroids, topical immunosuppresant, systemic steroids, phototherapy, and surgery.

The aim of this study is to investigate the effect of phototherpy and accupuncture combined therapy for vitiligo patients.

Enrollment: 9 patients

Sex: All

Ages: 20 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

Clinical diagnosis of Vitiligo

Exclusion criteria

• pregnancy
• immune disorder
• infection
• other dermatosis in treating areas

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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9 participants in 2 patient groups, including a placebo group

needling

Active Comparator group

Description:

needling + phototherapy

Treatment:

Device: Surrounding needling+ phototherapy

phototherapy

Placebo Comparator group

Description:

phototherapy

Treatment:

Device: phototherapy