The Effect of Video and Traditional Laryngoscopy on Hemodynamic Response in Hypertensive and Normotensive Patients

Aydin Adnan Menderes University

Status: Completed

Conditions: Hypertension; Intubation; Anesthesia

Treatments: Device: Macintosh laryngoscopy; Device: C-Mac Videolaryngoscope

Study type: Interventional

Funder types: Other

Identifiers

NCT03376828

2016/855

Details and patient eligibility

About

During endotracheal intubation, it is known that la laryngoscopy has significant effects, such as tachycardia and blood pressure increase, which may be harmful, especially in those with cardiovascular disease. Different studies comparing laryngeal stimulation and there resulting hemodynamic response made with various intubation devices are available in the literature. The investigators planned to work with the hypothesis that endotracheal intubation with videolaryngoscopy would have less hemodynamic response traditional (Macintosh) laryngoscopy and the use of videolaryngoscopy would result in wider vision with less laryngeal stimulation.

Full description

In this study, in a study on endotracheal intubation under general anesthesia, a routine preparation of endotracheal intubation using video laryngoscopy or Macintosh laryngoscopy in adult hypertensive and normotensive patients between 18-75 years old, form will be written and recorded.

Patient age, weight, height, sex, operation, co-morbid conditions and vital findings, measurements used in airway evaluation, initial trial success, laryngoscope using number of procedures, intubation tube number will be recorded.

Statistical analysis was performed using statistical program to compare the hemodynamic response of hypertensive and normotensive patients using videolaryngoscope or Macintosh laryngoscope

Enrollment: 200 patients

Sex: All

Ages: 18 to 75 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age: 18-75 years.
• Underwent surgery under general anesthesia.

Exclusion criteria

• ASA (American Society of Anesthesiologists) IV, V patients
• Preoperative systolic blood pressure 180 mmHg, diastolic blood pressure a pressure above 110 mmHg.
• Ejection fraction is less than 40%.
• Difficult intubation history
• Mallampati 3,4

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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200 participants in 4 patient groups

Hypertensive T group

Active Comparator group

Description:

Hypertensive T group: Patients participating in the study were randomly assigned hypertensive (preoperative systolic blood pressure \<180 mmHg and diastolic blood pressure \<100 mmHg) Macintosh laryngoscopy using intubated

Treatment:

Device: Macintosh laryngoscopy

Hypertensive VL group

Active Comparator group

Description:

Hypertensive VL group: Patients participating in the study were randomly assigned hypertensive (preoperative systolic blood pressure \<180 mmHg and diastolic blood pressure \<100 mmHg) C-Mac Videolaryngoscope using intubated

Treatment:

Device: C-Mac Videolaryngoscope

Non-hypertensive T group

Sham Comparator group

Description:

Non-hypertensive T group: (Preoperative systolic blood pressure \< 140 mmHg and diastolic blood pressure \< 100 mmHg) Macintosh laryngoscopy using intubated

Treatment:

Device: Macintosh laryngoscopy

Non-hypertensive VL group

Sham Comparator group

Description:

Non-hypertensive VL group: Preoperative systolic blood pressure \< 140 mmHg and diastolic blood pressure \< 100 mmHg C-Mac Videolaryngoscope using intubated

Treatment:

Device: C-Mac Videolaryngoscope