The Effect of Violet Device Dosed Ultra Violet-C Light (UV-C) Exposure on Healthy Hand Skin

University of Michigan

Status: Active, not recruiting

Conditions: Healthy Volunteers

Treatments: Device: Ultraviolet Light (UV-B); Device: Ultraviolet lights (UV-C)

Study type: Interventional

Funder types: Other

Identifiers

NCT05313555

HUM00198624

Details and patient eligibility

About

The purpose of this trial is to determine the safety of ultraviolet light (UV-C) irradiation as a method to sanitize hands instead of chemical-based sanitizers.

Eligible participants will be enrolled and receive treatment with the Violet UV-C device or UV-B. Punch biopsies will be performed following UV exposure to quantify any changes in cellular and molecular properties of the tissue.

Enrollment: 30 estimated patients

Sex: All

Ages: 18 to 55 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria

• Good general health
• Type 1 or type 2 skin (lightly colored skin)
• No history of skin disorders, disease states or physical conditions which would impair evaluation of the test sites
• Willingness and ability to follow the protocol
• No use of lotion or hand sanitizer 3 hours before the experiment

Exclusion Criteria:

• Has received an experimental drug or used an experimental device in the 30 days prior to admission to the study
• Undergoing treatment or taking medication that increases sun sensitivity
• History of keloids
• History of sensitivity to lidocaine or epinephrine
• Pregnant or nursing women, pregnancy status will be self-reported, women unsure of their pregnancy status will be excluded

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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30 participants in 2 patient groups

Ultraviolet lights (UV-B)

Active Comparator group

Treatment:

Device: Ultraviolet Light (UV-B)

Ultraviolet lights (UV-C)

Experimental group

Treatment:

Device: Ultraviolet lights (UV-C)