THE EFFECT OF VITAMIN C ON POST-ORTHODONTIC TREATMENT RELAPSE

Nourhan M.Aly

Status and phase: Enrolling; Phase 3; Phase 2

Conditions: Orthodontic Relapse

Treatments: Biological: Oral Vitamin C supplement; Biological: Local Vitamin C injection

Study type: Interventional

Funder types: Other

Identifiers

NCT06146296

#10/23

Details and patient eligibility

About

The aim of this study is to evaluate and compare the effect of locally injected and orally administered (systemic) Vitamin C on post-orthodontic treatment relapse

Enrollment: 36 estimated patients

Sex: All

Ages: 19 to 25 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients who were indicated for non-extraction orthodontic treatment.
• Adult patients with finished orthodontic treatment, using fixed appliance therapy.
• Patients with good oral hygiene, and a healthy periodontal condition.

Exclusion criteria

• Patients who received sectional fixed appliance therapy.
• Patients with hypodontia requiring tooth replacement in the retainer, as a temporary measure.
• Patients requiring fixed bonded retainers.
• Pregnant and lactating women.
• Patients with hereditary hemochromatosis.
• Cancer patients, receiving chemotherapy.
• Patients with chronic diseases such as diabetes, or those receiving drugs such as corticosteroids, both of which that may affect tooth movement.

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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36 participants in 3 patient groups

Intra-epidermal Vitamin C injection

Experimental group

Treatment:

Biological: Local Vitamin C injection

Oral Vit-C supplement

Active Comparator group

Treatment:

Biological: Oral Vitamin C supplement

Control group

No Intervention group