The Effect of Vitamin c on Preventing Complex Regional Pain Syndrome (CRPS Type I) Following Ankle Fracture

Clalit Health Services

Status: Unknown

Conditions: Ankle Fracture

Treatments: Drug: placebo; Dietary Supplement: vitamin c

Study type: Interventional

Funder types: Other

Identifiers

NCT01338129

RMC116131CTIL

Details and patient eligibility

About

The use of prophylactic treatment with vitamin c may prevent complex regional pain syndrome (CRPS)

Full description

There are several studies similar in wrist fracture.

Enrollment: 100 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• ankle fracture within 3 weeks after the fracture

Exclusion criteria

• pregnant or lactating woman
• open fracture
• already treated with vitamin c
• chronic renal failure

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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100 participants in 2 patient groups, including a placebo group

vitamin c

Experimental group

Description:

administration of vitamin c for 45 days following ankle fracture operation

Treatment:

Dietary Supplement: vitamin c

placebo

Placebo Comparator group

Description:

placebo pills

Treatment:

Drug: placebo