The Effect of Weight Loss on Ovarian Reserve

Clalit Health Services

Status: Unknown

Conditions: Weight Loss

Treatments: Dietary Supplement: weight loss

Study type: Observational

Funder types: Other

Identifiers

NCT01844128

0257-12mmc

Details and patient eligibility

About

Obesity affects on fertility. Obese women have lower pregnancy rate after infertility treatments.They need more doses of hormone during ovarian stimulation, more days for stimulation. During IVF treatment less oocytes are collected and the quality of embryo also harmed.

The first line treatment for those women with obesity and infertility is weight loss.

The investigators' hypothesis is that weight reduction improves ovarian reserve and fertility treatment outcome.

Full description

The investigators have outpatient clinic for obesity and infertility. the patients undergoing program of 3 months with diet and physical activity. Blood sample will take at the beginning of the program and at the end. The blood sample will evaluate for: AMH, Adiponectin, Leptin, CRP, Colesterol, CRP, Smac in addition TVUS will perform to evaluate AFC.

Enrollment: 100 estimated patients

Sex: Female

Ages: 18 to 43 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• undergoing weight loss program

Exclusion criteria

• dropp out before comletion the weighy loss target

Trial design

100 participants in 1 patient group

overweight women with infertility

Treatment:

Dietary Supplement: weight loss