The Effect of When Medication is Taken on Nutritional Status in Hospitalized Patients Older Than 65 Years (MEDICANUT2)

University Hospital Center (CHU) Dijon Bourgogne

Status

Completed

Conditions

Nutritional Status

Treatments

Biological: Blood sample

Other: western blot

Other: Flow cytometry

Study type

Observational

Funder types

Other

Identifiers

NCT02894827

VAN WYMELBEKE 2015

Details and patient eligibility

About

Polypathology in elderly subjects requires polypharmacy but even though the efficacy of a medication and digestive tolerance are ensured, the medication can be taken a long time from meals to reduce its side-effects. Despite numerous studies that have investigated links between medication and malnutrition, none have assessed the influence of the time the drug is taken on the evolution of the nutritional status of elderly hospitalized persons. So as to identify the best nutritional criterion in hospitalized persons, a retrospective pilot study will be conducted in about thirty patients. Their medication will be recorded and their nutritional status will be evaluated using the Geriatric Nutritional Risk Index (GNRI), albumin, prealbumin levels, weight and the Mini Nutritional Assessment (MNA) short form.

This preliminary study will allow us to choose the best nutritional criterion to compare the impact of two strategies for taking medication (post prandial versus pre-prandial) on improving the nutritional status of malnourished elderly hospitalized patients taking multiple drugs.

Enrollment

30 patients

Sex

All

Ages

65+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

patients aged 65 years or more.
patients with a stable or controlled acute disease hospitalized in a geriatric follow-up care unit.
patients whose life expectancy is greater than 30 days.
patients able to eat food normally.
patients able to swallow their medication.
patients with at least 3 drugs to be taken orally per day, not including oral nutritional supplements.

Exclusion criteria

patients at the end of life.
patients whose drugs must be taken before meals like Non-steroid anti-inflammatory drugs (NSAIDs), glinides, oral antidiabetic agents (OAD).
patients with parenteral and/or enteral nutrition in the period preceding admission to the geriatric unit.
patients with indications for parental and/or enteral nutrition.