The Effect of Whole Blood Viscosity on Contrast-Induced Nephropathy Development in Patients Undergoing Percutaneous Coronary Intervention

Bursa Postgraduate Hospital

Status: Completed

Conditions: Percutaneous Coronary Intervention Patients

Treatments: Other: Blood Viscosity Testing

Study type: Observational

Funder types: Other

Identifiers

NCT04703049

YİEAH

Details and patient eligibility

About

In our study, we aimed to investigate how whole blood viscosity (WBV) affects the development of contrast-induced nephropathy (CIN) in patients undergoing percutaneous coronary intervention (PCI).

Full description

In our study, 500 patients who applied to the cardiology clinic and underwent PCI for elective procedure, ST segment elevation myocardial infarction (STEMI), and non-STEMI were prospectively included. Before the procedure, we calculated WBV using the formula [(0.12 × hematocrit) + (0.17 × (total protein - 2.07)]. We defined CIN as the absolute (≥0.5 mg/dl) or relative increase (≥25%) in serum creatinine 48-72 h after exposure to a contrast agent compared with baseline serum creatinine values.

Enrollment: 500 patients

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients between ages 18 and 90
• underwent PCI in our hospital between

Exclusion criteria

• Patients with chronic kidney disease (CKD) who underwent hemodialysis or peritoneal dialysis
• Patients who underwent to coronary bypass surgery within 48 h were excluded from the study.