The Effect of Wild Blueberry Consumption on Glucose Regulation in Healthy Adults

University of Prince Edward Island

Status: Completed

Conditions: Diabetes

Treatments: Other: Blueberry; Other: Placebo

Study type: Interventional

Funder types: Other

Identifiers

NCT03192605

UPEI

Details and patient eligibility

About

The objective of the study is to determine how wild blueberry consumption affects glucose regulation, gastrointestinal hormones and satiety in healthy adults.

Full description

Healthy men and women (ages 21 - 65 years) were recruited to take part in a randomized, placebo controlled crossover design study. Subjects were screened to determine their health status (e.g. height, weight, body mass index, blood pressure and medical history). Subjects were randomly assigned to a sequence of two treatments with two study periods. The treatments are frozen wild blueberries and a placebo developed to match calories and fiber of the frozen wild blueberries. The subjects were asked to avoid high polyphenol foods in their typical diet for 7 days and consume one of the two treatments as a dietary intervention. After the seventh day subjects consumed a test meal along with either the wild blueberry or placebo. Blood was collected to determine glucose and satiety hormone levels.

Enrollment: 17 patients

Sex: All

Ages: 21 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Male or female

Exclusion criteria

• BMI < 20 and > 30 kg/m²
• Pregnant women or women who plan on becoming pregnant during the study
• Postpartum women
• Lactating women
• Diabetes Mellitus
• Kidney disease
• Liver disease
• GI Disease
• Certain cancers
• Smokers
• Blueberry allergies

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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17 participants in 2 patient groups, including a placebo group

Blueberry

Experimental group

Description:

150 grams wild blueberries

Treatment:

Other: Blueberry

Placebo

Placebo Comparator group

Description:

Placebo control

Treatment:

Other: Placebo