The Effect of「GTT-EGCG」on Acne Women

National Yang Ming Chiao Tung University

Status: Unknown

Conditions: Acne Lesion Counts

Treatments: Dietary Supplement: green tea extract EGCG

Study type: Interventional

Funder types: Other

Identifiers

NCT01846338

TCHIRB1010505

Details and patient eligibility

About

The aim of this study is to investigate the therapeutic effects of green tea extract on acne treatment and related hormone peptides by a double-blinded, randomized and controlled clinical trial.

Full description

change in acne lesions counts, hormone, quality of life

Enrollment: 80 estimated patients

Sex: Female

Ages: 20 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Female patient
• 20 to 45 years of age
• moderate or severe acne vulgaris as defined by the Investigator's Global Assessment (IGA; score of 3 or 4 on a scale from 0 to 5)

Exclusion criteria

• Received systemic retinoid or hormone treatment in the previous 3 months.
• Abnormal liver enzymes or kidney function tests (1.5 times higher than the upper normal limit)
• abnormal blood chemistry
• Pregnant or breast feeding women or the intention of becoming pregnant
• Concurrent systemic illness
• PCOS
• Very severe acne(IGA score5)

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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80 participants in 2 patient groups, including a placebo group

green tea extract EGCG

Experimental group

Description:

experimental: green tea extract EGCG, 500mg , tid, 4 weeks

Treatment:

Dietary Supplement: green tea extract EGCG

cellulose

Placebo Comparator group

Description:

Placebo Comparator: cellulose, 500 mg tid, 4 weeks

Treatment:

Dietary Supplement: green tea extract EGCG