The Effectiveness of a Novel Lip Product Containing Caulerpa Lentillifera Extract for Reducing Lip Hyperpigmentation

Chulalongkorn University

Status: Enrolling

Conditions: Hyperpigmentation

Treatments: Other: Lip product

Study type: Interventional

Funder types: Other

Identifiers

NCT07067879

HREC-DCU2025-037

Details and patient eligibility

About

The goal of this clinical trial is to evaluate the efficacy of the novel lip product containing Caulerpa lentillifera extract on the appearance and perception of dark lips in Thai adults aged 18 to 60 who report concerns about darkened lips. The main question it aims to answer is: Can the novel lip product containing C. lentillifera extract will significantly improve the appearance and perception of dark lips in Thai adults by reducing hyperpigmentation compared to baseline measurements?

Participants will apply the lip product twice a day, in the morning after breakfast and before bedtime, and refrain from using other lip products throughout the clinical trial period (7 days).

Researchers will compare the result to baseline measurements

Enrollment: 30 estimated patients

Sex: All

Ages: 18 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Understand the study protocol and provide informed consent after being informed of potential risks and benefits.
• Refrain from using any other lip products, including lipstick, lip gloss, or lip conditioners, during the study period.

Exclusion criteria

• Have a known allergy or sensitivity to cosmetic products or Caulerpa lentillifera.
• Are on medication one month prior to study commencement.
• Exhibit lip abnormalities such as malformation, inflammation, swelling, or sores.

Trial design

Primary purpose: Supportive Care

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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30 participants in 1 patient group

Lip product application group

Experimental group

Treatment:

Other: Lip product