The Effectiveness of Bu Zhong Yi Qi Tang in Patients with Myasthenia Gravis

Cheng, yu-ting

Status: Enrolling

Conditions: Myasthenia Gravis

Treatments: Drug: Bu Zhong Yi Qi Tang; Drug: caramel dyed starch placebo

Study type: Interventional

Funder types: Other

Identifiers

NCT06881173

20220305R

Details and patient eligibility

About

Research Background: According to the Myasthenia Gravis Foundation of America (MGFA, 2015), the estimated prevalence of myasthenia gravis is 14-20 per 100,000 people, with a higher prevalence in young female individuals compared to males. However, as individuals age, especially after the age of 50, the prevalence in males becomes higher than in females. myasthenia gravis patients often experience varying degrees of disability, leading to the need for long-term medical care, medication, and lifestyle adjustments. This also gives rise to subsequent challenges in caregiving, affecting both the patients' families and society.

Full description

:This study aims to assess the effectiveness of using a combination of traditional Chinese and Western medicine,to improve the meridian energy and autonomic nervous system function of myasthenia gravis patients.

Enrollment: 112 estimated patients

Sex: All

Ages: 20+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients diagnosed with ocular myasthenia by a doctor
• Western medicine prescriptions only take oral Mestinon (Pyrido stigmine Bromide)
• Patients over 20 years old
• Can understand and understand Those who can speak Mandarin or Taiwanese
• those with a clear state of consciousness and no diagnosis of mental illness
• patients and their families who are willing to receive precise integrated treatment of traditional Chinese and Western medicine.

Exclusion criteria

• Patients with liver failure or kidney failure
• Allergy symptoms to traditional Chinese medicine, such as skin itching and redness
• Patients with malignant tumors
• Patients currently undergoing radiotherapy and chemotherapy
• Pregnant
• Cardiac rhythm device implementer

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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112 participants in 2 patient groups, including a placebo group

Experimental group

Experimental group

Description:

Have taken Bu Zhong Yi Qi Tang

Treatment:

Drug: Bu Zhong Yi Qi Tang

control group

Placebo Comparator group

Description:

Have taken caramel dyed starch placebo

Treatment:

Drug: caramel dyed starch placebo