The Effectiveness of Buccal Infiltration Only Using Articaine for Extraction of Mandibular Molar

Riyadh Elm University

Status and phase: Not yet enrolling; Phase 4

Conditions: Pain

Treatments: Drug: Articaine 4%/Epi 1:100000 Inj Cart 1.7Ml; Drug: Lidocaine 2%/Epi 1:100000 Inj Cart 1.7Ml

Study type: Interventional

Funder types: Other

Identifiers

NCT06161714

FPGRP/2023/791/1041

Details and patient eligibility

About

The goal of this clinical trial, is to test out the efficacy of using Articaine only as a local anesthesia as buccal infiltration to extract lower molar teeth.

Study will be performed in patients visiting Riyadh Elm University clinics seeking extraction of lower molars bilaterally, in each visit one molar tooth will be extracted using Ariticaine and the second visit with Lidocaine, pain level will be monitored and documented.

This study may be helpful in providing scientific information to the oral maxillofacial surgeons which will assist them in choosing the best local anesthetic agent, and possibly substituting using inferior alveolar nerve block with infiltration only when extracting the mandibular posterior teeth.

Full description

This is a double-blind, randomized clinical trial, which will involve 40 patients visiting the out-patient department of Oral and Maxillofacial surgery. For each patient, one mandibular molar will be extracted from right as well as left side, with one side being anesthetized using 4% articaine with 1:100,000 epinephrine and other with 2% lidocaine with 1:100,000 epinephrine buccal infiltration only. Evaluation and comparison will be done on the basis of pain prevalence exhibited by the patients while extraction.

Enrollment: 40 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Male and female patients
• Patients with age more than 18 years
• Patients indicated for at least one mandibular molar extraction
• Patients with the ability to fill the questionnaire

Exclusion criteria

• Patients with abscess or any lesion, which may affect the local anesthesia provision.
• Patients with stage III mobile teeth
• Patients with a history of medical conditions such as diabetes mellitus, heart disease, pregnancy, allergy or renal disease
• Patients who are not able to give an informed consent or are not agreeing to take part in this study

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Double Blind

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40 participants in 2 patient groups

Right mandibular molar

Experimental group

Description:

Articaine 4% with 1:100,000 epinephrine

Treatment:

Drug: Articaine 4%/Epi 1:100000 Inj Cart 1.7Ml

Left mandibular molar

Experimental group

Description:

Lidocaine 2% with 1:100,000

Treatment:

Drug: Lidocaine 2%/Epi 1:100000 Inj Cart 1.7Ml