The Effectiveness of Bupivacaine and Bupivacaine+Dexmedetomidine Combination in Transversus Abdominis Plane* Block (TAP)

Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital

Status: Not yet enrolling

Conditions: Colorectal Neoplasms; Colorectal Cancer

Treatments: Drug: Bupivacain; Drug: bupivacain+dexmedetomidine

Study type: Observational

Funder types: Other

Identifiers

NCT06370949

2024-01/17

Details and patient eligibility

About

Transversus abdominis plane (TAP) block is an anesthesia method that provides somatic analgesia to the anterior and lateral abdominal walls. Thus, TAP block is widely implemented in perioperative management of colorectal cancer patients.

Researchers aimed to evaluate the analgesic effectiveness and duration of effect of dexmedetomidine added to bupivacaine in the TAP block applied in colorectal cancer surgeries.

Full description

Transversus abdominis plane (TAP) block is an anesthesia method that provides somatic analgesia to the anterior and lateral abdominal walls. With the increasing use of ultrasound guidance during peripheral nerve blocks, trunk blocks such as the transversus abdominis plane (TAP) block are widely used for analgesia after abdominal surgery.

The advantages of TAP block include being less invasive than epidural analgesia, lower incidence of hypotension, and shorter hospital stay. Due to these advantages, TAP block has become a widely preferred method.

Researchers aimed to evaluate the analgesic effectiveness and duration of effect of dexmedetomidine added to bupivacaine in the TAP block applied in colorectal cancer surgeries. The study will be conducted in a tertiary oncology hospital in Turkey and 84 colorectal cancer patients will be included.

Enrollment: 84 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• colorectal cancer diagnosis
• undergoing colorectal cancer surgery

Exclusion criteria

• allergic reaction to local anesthetics
• bleeding anomalies
• infection in TAP block area

Trial design

84 participants in 2 patient groups

bupivacaine

Description:

Ultrasonography (USG) guided bilateral TAP block:20 ml %0,25 concentration bupivacain

Treatment:

Drug: Bupivacain

bupivacaine+dexmedetomidine

Description:

Ultrasonography (USG) guided bilateral TAP block: 20 ml %0,25 concentration bupivacain+ 0.5 mcg/kg dexmedetomidine

Treatment:

Drug: bupivacain+dexmedetomidine