The Effectiveness of Coconut Oil Cream as a Prevention Treatment for Occupational Hand Dermatitis Among Batik Workers

University of Indonesia (UI)

Status and phase: Completed; Phase 3

Conditions: Hand Dermatoses

Treatments: Drug: Cocos Nucifera Whole

Study type: Interventional

Funder types: Other

Identifiers

NCT03617068

05

Details and patient eligibility

About

Empirically, mosturizer is used to prevent and treat many occupational dermatoses that has skin barrier impairment. Evidence based medicine about the effectivity of mosturizer in occupational dermatoses is limited. Coconut oil is one of traditional substance that is used as a skin care. There is study shows that coconut oil is effective for atopic dermatitis treatment in children. Other studies are needed to assess the effectivity coconut oil mosturizer cream to overcome occupational hand dermatitis.

Full description

The aim of this study is to measure the effectivenes of coconut oil cream for batik workers who suffer from occupational hand dermatitis. The gloves that used as a protective equipment are made from rubber which have its own limitations. Therefore other interventions are needed to improve barrier skin.

Enrollment: 32 patients

Sex: Male

Ages: 25 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• signing the informed consent document before the study start
• adult population include patients between the ages of 18 and 64 years who work in the dyeing and washing process more than 6 months.
• suffering from occupational hand dermatitis that meet Mathias Criteria.
• willing to obey the research protocol
• willing to fill in diary periodically

Exclusion criteria

• having history of allergy or irritation caused by coconut oil or other mosturizer
• suffering from symptoms including edema, exudation, crust, fissures, liver problems, and signs of infection
• on corticosteroid treatment ( medium to high potency) or on systemic immunosuppressive therapy

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Double Blind

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32 participants in 2 patient groups, including a placebo group

Coconut Oil Cream

Active Comparator group

Description:

This group consist of batik traditional workers who use coconut oil cream for 2 weeks.

Treatment:

Drug: Cocos Nucifera Whole

Drug: Cocos Nucifera Whole

Placebo Cream

Placebo Comparator group

Description:

This group consist of batik traditional workers who use placebo cream which contained the vehiculum of the cream; using for 2 weeks.

Treatment:

Drug: Cocos Nucifera Whole

Drug: Cocos Nucifera Whole