The Effectiveness of Global Postural Reeducation on Alzheimer Disease Patients (GPR)

Universidad Católica San Antonio de Murcia

Status: Completed

Conditions: Alzheimer's Type Dementia; Cognitive Decline; Postural; Strain

Treatments: Other: GPR Intervention Research group

Study type: Interventional

Funder types: Other

Identifiers

NCT03732053

BJ8674287

Details and patient eligibility

About

This research study is developed on an experimental design with randomized controlled intervention were participated 135 subjects with AD including 45 of the control group. It lasted 6 months with pre-post tests (T0-T1) executed before and after six months of treatment. By having in focus the evaluation of GPR therapy effects on cognitive, proprioceptive, depressive, autonomy, gait and life quality of the above mentioned subjects.

Full description

In order to assess the cognitive abilities of the patients a cognitive test was administered which acts through a scale concerning depression and mood evaluation as well as a questionnaire was developed aiming to evaluate the examined subjects' functional abilities: Mini Mental State Examination (MMSE), Quality of Life in Alzheimer Disease (QoL-AD), geriatric Depression Scale (GDS), Barthel Index (BI), Neuropsychiatric Inventory (NPI), Tinetti Scale (TS).

Enrollment: 135 patients

Sex: All

Ages: 40 to 95 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Clinical diagnosis of Alzheimer's Disease
• Older than 40 years of age
• Male and female
• Intellectual disability
• Cognitive impairment
• Able to do daily activities on his own
• No presence of any other neurological and psychological disease
• No presence of brain tumors

Exclusion criteria

• No presence of Alzheimer's Disease
• Under 40 years old
• Presence of brain tumors
• Neurological patients
• Presence of psychiatric disease
• Depression symptoms
• Presence of neuromuscular disease
• Ictus
• Aggressive patients

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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135 participants in 2 patient groups

GPR Intervention Research group

Experimental group

Description:

A total of 135 subjects with AD in the mild or moderate phase participated in the study from which 90 pertain to research group.The intervention implemented to the patients with AD was the Global Postural therapy which lasted about 30-40 min in repeated sessions of 2 meetings per week by making 48 sessions in total during a six month period.

Treatment:

Other: GPR Intervention Research group

Control Group

No Intervention group

Description:

45 subjects of the study belongs to the control group which has not received the same treatment .