the Effectiveness of Intermittent Pneumatic Compression on Neuropathic Pain in Patients With Diabetic Polyneuropathy

Busra Gunes

Status: Completed

Conditions: Diabetic Neuropathic Pain

Treatments: Other: pregabalin group; Device: intermittent pneumatic compression +pregabalin group

Study type: Interventional

Funder types: Other

Identifiers

NCT06336486

BalikesirU-FTR-BG-01

Details and patient eligibility

About

In this study,the effectiveness of intermittent pneumatic compression therapy on neuropathic pain and quality of life in patients with neuropathic pain due to type 2 diabetes was investigated

Full description

The investigators conducted our research from 50 patients with type 2 diabetes of 5-20 years, who received pregabalin treatment with diabetic neuropathy with consent form between 40-75 years.The investigators divided the patients into two equal groups , some of the patients were given an intermittent pneumatic compression program at a pressure of 35 mmhg for 30 min to the lower extremity for 10 days of extreme alternation in our clinic and pregabalin treatment was continued,only pregabalin treatment of the other group was continued. VAS, PQAS, LANSS, SF-36 were evaluated.The evaluation was done before the treatment, at the end of the intermittent pneumatic compression treatment(approximately 2 weeks after the start of the treatment) and 3 months later.

Enrollment: 50 patients

Sex: All

Ages: 40 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 5-20 years history of type 2 diabetes
• Between the ages of 40-75
• Body mass 25-40
• Blood pressure 100/60-140/90
• Patient diagnosed with diabetic polyneuropathy
• Use of pregabalin

Exclusion criteria

• Connective tissue disease
• Peripheral nerve vasculitis
• Postherpetic neuralgia
• Alcoholic neuropathy
• Autonomic neuropathy
• Chronic renal failure
• Charcot-marie tooth disease

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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50 participants in 2 patient groups

intermittent pneumatic compression +pregabalin

Active Comparator group

Description:

Patients were given an intermittent pneumatic compression program at a pressure of 35 mmhg for 30 min to the lower extremity for 10 days of extreme alternation in our clinic and pregabalin treatment was continued.

Treatment:

Device: intermittent pneumatic compression +pregabalin group

pregabalin

Other group

Description:

only pregabalin treatment was continued.

Treatment:

Other: pregabalin group