The Effectiveness of Non-Invasive Ventilation Use in Preterm Infants.

Hospital General Universitario Gregorio Marañon

Status: Completed

Conditions: Noninvasive Ventilation; Preterm Infants

Treatments: Other: Preterm Infants treated with non-invasive ventilation.

Study type: Observational

Funder types: Other

Identifiers

NCT02628821

02/2015

Details and patient eligibility

About

Prospective observational study of SNIPPV use in preterm infants of less than 32weeks of gestation from January 2012 to December 2015. Previous respiratory status is analyzed as well as respiratory outcomes and possible secondary side effects.

SNIPPV is used to prevent Intubation in Infants in which nCPAP has already failed (Infants that met intubation criteria) and also is used electively for extubation when nCPAP extubation has previously failed or infants with Prolonged mechanical ventilation (more than 15 days) with high respiratory parameters (PMAP > 10 cmH2O and FiO2>35%).

Full description

SNIPPV is used to prevent Intubation in Infants in which nCPAP has already failed (Infants that met intubation criteria) and also is used electively for extubation when nCPAP extubation has previously failed or infants with Prolonged mechanical ventilation (more than 15 days) with high respiratory parameters (PMAP > 10 cmH2O and FiO2>35%).

Enrollment: 45 patients

Sex: All

Ages: 1 minute to 3 months old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• Preterm Infants of less than 32 weeks of GA in which SNIPPV is applied for nCPAP failure.
• Preterm Infants of less than 32 weeks of GA in which SNIPPV is applied electively for extubation.

Exclusion Criteria: None

Trial design

45 participants in 1 patient group

Preterm Infants treated with non-invasive ventilation

Description:

Preterm Infants of less than 32 weeks of Gestational age treated with synchronized non-invasive ventilation (SNIPPV) to prevent intubation or extubation failure based in a prospective protocol: * nCPAP failure: Preterm infants supported with nCPAP that meet intubation criteria if they are in a stable situation. * Electively For extubation: Preterm infants in which nCPAP extubation has previously failed or Prolonged mechanical ventilation (more than 15 days) with high respiratory parameters (PMAP \> 10 cmH2O and FiO2\>35%).

Treatment:

Other: Preterm Infants treated with non-invasive ventilation.