The Effectiveness of Single Antibiotic Paste Nitrofurantoin Versus Double Antibiotic Paste

Altamash Institute of Dental Medicine

Status and phase: Completed; Phase 4

Conditions: Symptomatic Irreversible Pulpitis; Pain

Treatments: Drug: Nitrofurantoin; Drug: Double Antibiotic

Study type: Interventional

Funder types: Other

Identifiers

NCT05600023

Intracanal medication

Details and patient eligibility

About

In our study, we used nitrofurantoin as a root canal medication in patients suffering from symptomatic irreversible pulpitis in alleviating pain compared with double antibiotic paste.

Full description

This study aims to compare the efficacy in alleviating pain between intracanal medicaments Nitrofurantoin versus double antibiotic paste.

Enrollment: 60 patients

Sex: All

Ages: 18 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• No medical history
• no history of allergy to medications used in root canal treatment
• patients suffering from Symptomatic Irreversible Pulpitis

Exclusion criteria

• Patients who were not suitable for conventional root canal treatment
• multirooted teeth

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

---

60 participants in 3 patient groups

Nitrofurantoin

Experimental group

Treatment:

Drug: Nitrofurantoin

Double antibiotic paste

Experimental group

Treatment:

Drug: Double Antibiotic

Control

No Intervention group