The Effectiveness of Two Osteoporosis Drugs on Prosthetic Bone Mineral Density (BMD) Loss After Total Hip Arthroplasty(THA) (ETOD)

Yokohama City University Medical Center

Status: Unknown

Conditions: Arthroplasty, Replacement, Hip; Bone Density

Treatments: Drug: alendronate, alfacalcidol

Study type: Interventional

Funder types: Other

Identifiers

NCT01020253

YCU07-122

Details and patient eligibility

About

The purpose of this study is to evaluate whether alendronate and alfacalcidol are effective on prosthetic or lumbar spine BMD after total hip arthroplasty.

Enrollment: 60 patients

Sex: All

Ages: 44 to 82 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• osteoarthritis of the hip
• patients after total hip arthroplasty

Exclusion criteria

• diseases related to bone metabolism
• patients taking drugs which affect bone metabolism

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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60 participants in 3 patient groups

Alendronate medication

Active Comparator group

Treatment:

Drug: alendronate, alfacalcidol

Alfacalcidol medication

Active Comparator group

Treatment:

Drug: alendronate, alfacalcidol

Non-medication

No Intervention group

Treatment:

Drug: alendronate, alfacalcidol