The Effects of a Combined Exercise Training Program on Vascular Health and Metabolic Profile in Obese Adolescent Girls.

Pusan National University

Status: Completed

Conditions: Obesity, Adolescent

Treatments: Behavioral: Combined Exercise Training

Study type: Interventional

Funder types: Other

Identifiers

NCT03146026

PusanNU-2

Details and patient eligibility

About

The purpose of this study was to examine the impact of 12 weeks of combined exercise training (CET) on arterial stiffness, endothelial function, inflammatory markers, insulin resistance, and body composition in obese adolescent girls. Thirty obese adolescent girls participated in this study. The girls were randomly divided into CET group (n=15) and control group (n=15). The CET group performed concurrent resistance training followed by aerobic training at 40-70% of the heart rate reserves (HRR) 3 days/week for 12 weeks. Plasma nitric oxide, endothelin-1, C-reactive protein, arterial stiffness, homeostasis model assessment of insulin resistance (HOMA-IR), glucose, insulin, and the adiponectin/leptin ratio were measured before and after the 12-weeks study.

Enrollment: 30 patients

Sex: Female

Ages: 14 to 16 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Obese with hyperinsulinemia
• Abdominal obesity
• Sedentary (no regular exercise training or physical activity)
• No weight loss diet during last 6 months.

Exclusion criteria

• Hypertension
• Pregnancy
• Chronic disease

Trial design

Primary purpose: Health Services Research

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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30 participants in 2 patient groups

No Exercise (CON)

No Intervention group

Description:

Fifteen obese adolescent girls. This arm did not perform any exercise training for 12 weeks. Caloric intake was 1921.7 kcal/day.

Combined Exercise Training (CET)

Experimental group

Description:

Fifteen obese adolescent girls. This arm performed combined exercise training 3 times per a week for 12 weeks. Caloric intake was 1921.7 kcal/day.

Treatment:

Behavioral: Combined Exercise Training