The Effects of a Fiber-enriched Bakery Product on Glucose, Insulin Values and Appetite

University of Turin

Status: Completed

Conditions: Healthy

Treatments: Other: Enriched panettone; Other: Panettone standard

Study type: Interventional

Funder types: Other

Identifiers

NCT06032260

PAN_2023

Details and patient eligibility

About

The aim of the present pilot randomized controlled trial is to compare the effects of the following: 1)-panettone enriched with arabinoxylans (p-rich), 2)-panettone not enriched (p-standard) on blood glucose and insulin values, and appetite scores in 10 healthy volunteers.

Full description

This is a crossover, randomized double-blind trial. A product enriched with arabinoxylan extracted from threshing (panettone, p-rich, a sweet baked product with a high glycemic index) was developed to assess the impact on metabolic responses and satiety when compared to the standard product (p-standard) .

Ten Caucasian non-smoker healthy adult volunteers were enrolled starting from January 2023.

Participants were randomized to receive either the p-rich or p-standard. The order of administration of each product was randomized using a computer-generated sequence. The day of each test, fasting individuals underwent a blood sample collection, and weight and height measurements. Then, participants consumed 100 grams of the product within 20 minutes, while sitting. Blood samples were collected at 15, 30, 45, 60, 90, 120 minutes after the consumption of each food.

Enrollment: 10 patients

Sex: All

Ages: 20 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• non-smokers healthy adults;
• age 20-65 years;
• ability to provide informed written consent

Exclusion criteria

• obesity;
• chronic diseases or pharmacological therapies;
• dietary restrictions;
• allergy or intolerance to the tested food

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Triple Blind

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10 participants in 2 patient groups

Enriched panettone

Experimental group

Description:

100 grams of panettone enriched with fiber. The added fiber is JAX Plus® (Heallo srl, Milano, Italy), a soluble fiber with Arabinoxylans from wheat and barley

Treatment:

Other: Enriched panettone

Panettone standard

Active Comparator group

Description:

100 grams of panettone without fiber enrichment

Treatment:

Other: Panettone standard