The Effects of a Ficus Carica in Subjects With Functional Constipation

Chonbuk National University

Status and phase: Completed; Phase 3; Phase 2

Conditions: Functional Constipation

Treatments: Dietary Supplement: Placebo (300g/day); Dietary Supplement: Ficus Carica (300g/day)

Study type: Interventional

Funder types: Other

Identifiers

NCT02138851

YGF-CON-FIG2

Details and patient eligibility

About

The investigators performed a 8-week, randomized, double-blind, placebo-controlled human trial to evaluate the efficacy and safety of Fig paste on functional constipation. The investigators measured colon transit time, frequency of defecation, defecation time, stool type, and abdominal discomfort.

Enrollment: 80 patients

Sex: All

Ages: 19 to 39 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• age between 19 and 39 years,
• diagnosis of functional constipation by ROME III criteria,
• Colon transit time (CTT) ≥ 36 h,
• subjects giving written informed consent

Exclusion criteria

• allergic or hypersensitive response to any of the ingredients in the test products,
• having previous history or current disease of digestive system, cardiovascular system, endocrine system and neurological disorder,
• diagnosis of irritable bowel syndrome by ROME III criteria, etc,.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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80 participants in 2 patient groups, including a placebo group

Ficus Carica

Experimental group

Description:

Ficus Carica 300g/day

Treatment:

Dietary Supplement: Ficus Carica (300g/day)

Placebo

Placebo Comparator group

Description:

Placebo 300g/day

Treatment:

Dietary Supplement: Placebo (300g/day)