The Effects of Aerobic Exercise in Microvascular Endothelium Function in Patients With Cardiovascular Diseases

Instituto Nacional de Cardiologia de Laranjeiras

Status: Completed

Conditions: Cardiovascular Diseases

Treatments: Behavioral: Exercise

Study type: Observational

Funder types: Other

Identifiers

NCT02514564

Faperj-E-26/101.575

Details and patient eligibility

About

This study evaluates the effects of different volumes of aerobic exercise training in cardiovascular parameters of patients with cardiovascular diseases enrolled in a cardiac rehabilitation program.

Full description

Aerobic exercise training is well known to improve endothelium dependent vasodilatation in the microcirculation. However, the impact of exercise frequency on this response in patients with coronary artery disease remains unclear.

Enrollment: 115 patients

Sex: All

Ages: 40 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• sedentarism for at least 6 months;
• clinical diagnosis for coronary artery disease (occurrence of any acute coronary syndrome, including ST elevation or non-ST elevation myocardial infarction or unstable angina or by the diagnosis of obstructive coronary artery disease on coronary angiography in patients with stable angina).

Exclusion criteria

• nephropathies;
• decompensated cardiovascular diseases;
• liver diseases.

Trial design

115 participants in 3 patient groups

2x/wk

Description:

This group will be consisted of patients that will perform exercise two times a week.

Treatment:

Behavioral: Exercise

3x/wk

Description:

This group will be consisted of patients that will perform exercise three times a week.

Treatment:

Behavioral: Exercise

Control

Description:

This group will not perform exercise.