The Effects of Aerobic Exercise Training on Cardiorespiratory Fitness in Stroke Patients

Gaziler Physical Medicine and Rehabilitation Education and Research Hospital

Status: Completed

Conditions: Stroke, Cardiovascular

Treatments: Other: The Effects of Aerobic Exercise Training on Cardiorespiratory Fitness, Functional Capacity, Balance and Ventricular Repolarization Indices in Stroke Patients

Study type: Interventional

Funder types: Other

Identifiers

NCT05058586

21

Details and patient eligibility

About

Background:

Aerobic exercise training has favorable effects on quality of life, motor recovery, and aerobic endurance after stroke.

Objectives: In this study, the investigators aimed to explore the effects of anti-gravity treadmill gait training and underwater walking therapy on cardiorespiratory fitness in stroke survivors.

Full description

Methods: Seventy patients with a history of stroke were admitted to our center between July 2017 and January 2018. Subjects who participated in the study were randomly assigned to anti-gravity treadmill training, underwater walking therapy, and control group. Investigators examined the aerobic capacity of participants by using the 6-minute walk test and cycle ergometer testing before starting the treatment along with a one-month follow-up. The patient's balance was examined by using the Berg Balance Scale (BBS).

Enrollment: 30 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients between the ages of 18 and 80 and diagnosed with stroke and time from stroke onset to admission were longer than three months
• Independent walking ability more than 10 meters with or without assistance
• Patients whose cognitive and functional status were suitable for the training program

Exclusion criteria

• Had a previous history of stroke
• Bilateral hemiplegia
• Leg-length difference >2.0 cm
• Fixed flexion contracture or severe joint deformity
• Bladder or bowel incontinence
• Open wound
• Cardiovascular complaints and can not tolerate exercise training
• Other neurological comorbidities including, multiple sclerosis (MS), spinal cord injury (SCI), traumatic brain injury (TBI), Parkinson's disease, and intracranial tumors
• Congestive heart failure
• Atrial fibrillation (AF), use of antiarrhythmic drugs affecting QT duration, any type of bundle branch block on electrocardiogram (ECG)

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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30 participants in 3 patient groups

Conventional theraphy group

Active Comparator group

Description:

13 patients received twenty sessions of conventional therapy for four weeks

Treatment:

Other: The Effects of Aerobic Exercise Training on Cardiorespiratory Fitness, Functional Capacity, Balance and Ventricular Repolarization Indices in Stroke Patients

Anti gravity treadmill training

Active Comparator group

Description:

13 patients received twenty sessions of conventional therapy for four weeks and Alter-G training was performed 3 days/week for 4 weeks, with up to 30 min. of training per session.

Treatment:

Other: The Effects of Aerobic Exercise Training on Cardiorespiratory Fitness, Functional Capacity, Balance and Ventricular Repolarization Indices in Stroke Patients

Underwater walking therapy group

Active Comparator group

Description:

13 patients received twenty sessions of conventional therapy for four weeks and three sessions of aerobic exercise treatment of 45 minutes per week underwater

Treatment:

Other: The Effects of Aerobic Exercise Training on Cardiorespiratory Fitness, Functional Capacity, Balance and Ventricular Repolarization Indices in Stroke Patients