The Effects of Audio-Based Therapy on Anxiety in Psoriasis (PsOUND-PSO)

University of California San Francisco (UCSF)

Status: Not yet enrolling

Conditions: Psoriasis (PsO); Anxiety

Treatments: Behavioral: Music Therapy; Behavioral: Pink Noise

Study type: Interventional

Funder types: Other

Identifiers

NCT07390487

PsOUND-PSO

Details and patient eligibility

About

Anxiety in psoriasis is associated with impaired quality of life, and the prevalence of anxiety symptoms in psoriatic populations is approximately 34% and anxiety disorders up to 16%. Many experts recommend routine screening, referral, and interventions for anxiety in psoriasis; however, many barriers inhibit access to mental health resources and proper management. To our knowledge, there is a lack of easily accessible interventions that manage anxiety. Audio-based therapy offers convenient and effective interventions that show reduced anxiety in published, randomized studies and is a promising management for psoriasis patients. This study will evaluate the effects of audio therapy in patients with psoriasis and measure changes in overall symptoms.

Enrollment: 120 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age ≥18 years
• Self-reported dermatologist-diagnosed psoriasis
• GAD 2-Item Score ≥1 at screening
• Ability to consent and complete pre- and post-intervention surveys.
• Internet access and the ability to use a computer/smartphone with headphones for a single 23-30 minute session at home.

Exclusion criteria

• Severe hearing impairment precluding headphone listening
• Any condition requiring strict sound avoidance (such as seizure/epilepsy, major head trauma, severe sound-triggered migraine) that would make participation unsafe.
• Other diagnoses that in the investigator's judgment preclude safe participation or interfere with anxiety or psoriasis evaluation.

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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120 participants in 2 patient groups

Music Therapy

Experimental group

Description:

Participants listen to the iso-principle music with added auditory beat stimulation playlist for 23-30 minutes.

Treatment:

Behavioral: Music Therapy

Pink Noise

Sham Comparator group

Description:

Participants listen to the pink noise playlist for 23-30 minutes.

Treatment:

Behavioral: Pink Noise