The Effects of Beta-glucan Enriched Oatcake Consumption on Metabolic Disease Risk Factors

Q

Queen Margaret University

Status

Unknown

Conditions

Cardiovascular Diseases
Metabolic Syndrome X

Treatments

Dietary Supplement: Beta-glucan enriched oatcake
Dietary Supplement: Isocaloric control

Study type

Interventional

Funder types

Other

Identifiers

NCT02615444
QueenMUsz

Details and patient eligibility

About

The purpose of this study is to determine whether daily consumption of soluble fibre, oat beta glucan (4g), for six weeks will have any impact on overweight/obese individuals in terms of risk factors used to define metabolic disease.

Full description

The purpose of this study is to determine whether daily consumption oat beta glucan (4g) for six weeks will have any impact on overweight/obese individuals in terms of risk factors used to define metabolic disease. Oat beta-glucan has been incorporated into a novel oatcake product manufactured by Nairn's Oatcakes Ltd. Consumption of the oatcake products will deliver enough oat-beta glucan to the diet to meet European Food Safety Authority health claims for lowering blood cholesterol and reducing post-prandial glycaemic responses.

Enrollment

90 estimated patients

Sex

All

Ages

18+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Males and females 18 years and older
  • Waist circumference measurements of ≥94cm for males and 80cm for females, or a body mass index of ≥30kg/m2
  • Individuals who are able to provide informed consent

Exclusion criteria

  • Postmenopausal females
  • Smokers
  • Individuals who suffer from, or taking medication for, cardiovascular or gastro-intestinal disease
  • Impaired glucose tolerance/Diabetes mellitus
  • Pregnancy or breastfeeding
  • Those who have high dietary fibre intakes (>20g/day)
  • Known food allergies to oats, wheat, lactose, or sesame seeds

Trial design

Primary purpose

Prevention

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Double Blind

90 participants in 2 patient groups, including a placebo group

Beta-glucan enriched oatcake
Experimental group
Description:
Oatcakes which have been enriched with beta-glucan. Each participant will consume 5 oatcakes daily in order to ingest 4g of oat-beta glucan.
Treatment:
Dietary Supplement: Beta-glucan enriched oatcake
Isocaloric control
Placebo Comparator group
Description:
Control: Wheat based snack, equicaloric and matched to intervention product for macronutrient content. Contains no oat-beta glucan. Each participant will consume 6.5 Krackawheats daily.
Treatment:
Dietary Supplement: Isocaloric control

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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