The Effects of Body Mass Index on Thoracic Paravertebral Block Analgesia

Ankara City Hospital

Status: Completed

Conditions: Thoracic Surgery, Video-Assisted; Thoracic Paravertebral Block; Pain, Postoperative; Body Mass Index; Acute Pain

Treatments: Procedure: Thoracic Paravertebral Block

Study type: Interventional

Funder types: Other

Identifiers

NCT05357976

E.Kurul-E1-22-2596

Details and patient eligibility

About

Obesity has become one of the world's leading health problems. It is known that obesity causes many diseases and negatively affects the quality of life. For this reason, many conditions that are thought to be effective in obesity and concern the quality of life of patients have been scientifically researched and continue to be investigated. One of them is postoperative pain. Although there are studies stating that there is no relationship between body mass index (BMI) and postoperative pain, when the literature data is examined, it is thought that obesity is a risk factor for postoperative pain and changes pain sensitivity and analgesic needs of patients. There are also studies in the literature stating that the level of postoperative pain increases in parallel with each unit increase in BMI.

After thoracic surgery, many analgesic methods have been suggested, including thoracic epidural analgesia (TEA), thoracic paravertebral block (TPVB), intercostal nerve blocks (ICSB), erector spina plane block (ESPB), serratus anterior plane block (SAPB). This study will compare the effects of BMI on postoperative pain in patients undergoing TPVB for postoperative analgesia and thoracoscopic surgery.

Enrollment: 75 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 18 to 80 years old
• ASA physical status I-II-III
• BMI 18 to 40 kg/m2
• Elective video-assisted thoracoscopic surgery

Exclusion criteria

• Patient refusing the procedure
• Emergency surgery
• Chronic opioid or analgesic use
• Patients who will operate under emergency conditions
• Patients who will not undergo VATS

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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75 participants in 3 patient groups

Patients with a BMI of 18-24.9 kg/m2

Active Comparator group

Description:

The needle will be advanced to the paravertebral area with an ultrasound-guided in-plane technique. 30 ml of 0.25% bupivacaine will be injected into this area.

Treatment:

Procedure: Thoracic Paravertebral Block

Patients with a BMI of 25-29.9 kg/m2

Active Comparator group

Description:

The needle will be advanced to the paravertebral area with an ultrasound-guided in-plane technique. 30 ml of 0.25% bupivacaine will be injected into this area.

Treatment:

Procedure: Thoracic Paravertebral Block

Patients with a BMI of 30-40 kg/m2

Active Comparator group

Description:

The needle will be advanced to the paravertebral area with an ultrasound-guided in-plane technique. 30 ml of 0.25% bupivacaine will be injected into this area.

Treatment:

Procedure: Thoracic Paravertebral Block