The Effects of Caffeine on Heart Rate and Heart Rate Variability

St Mary's University College

Status: Not yet enrolling

Conditions: Caffeine

Treatments: Drug: Caffeine; Drug: Placebo

Study type: Interventional

Funder types: Other

Identifiers

NCT05521386

StMarysUC5

Details and patient eligibility

About

In previous research we have shown that an acute caffeine dose of 5 mg/kg body mass reduces heart rate at rest and during low intensity exercise, with the effect dissipating as exercise intensity increases. If, as suspected, the effect at rest and at low intensities is due to an effect of caffeine on parasympathetic activity, this is likely to be reflected in an increase in heart rate variability (the beat-to-beat fluctuation in heart rate). The aim of this study is therefore to investigate the effect of caffeine on heart rate and heart rate variability at rest and during submaximal exercise.

Enrollment: 16 estimated patients

Sex: Male

Ages: 18 to 55 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Trained cyclists

Exclusion criteria

• Injured or a contraindicative medical condition

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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16 participants in 2 patient groups, including a placebo group

Caffeine

Experimental group

Description:

caffeine dose of 5 mg per kg of body mass administered orally via a gelatine capsule

Treatment:

Drug: Caffeine

Placebo

Placebo Comparator group

Description:

maltodextrin (placebo) dose of 5 mg per kg of body mass administered orally via a gelatine capsule

Treatment:

Drug: Placebo