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The Effects Of DBS Of Subthalamıc Nucleus On Functionality In Patıents With Parkinson's Disease: Short-Term Results

M

Mustafa Kemal University

Status

Unknown

Conditions

Surgery
Respiration; Decreased
Muscle Weakness
Parkinson Disease

Treatments

Device: MIP and MEP

Study type

Interventional

Funder types

Other

Identifiers

NCT03797976
Hatay Mustafa Kemal U 1

Details and patient eligibility

About

Parkinson's disease is a progressive chronic neurodegenerative disease. In cases where drug treatment is insufficient and drug use is not possible due to drug side effects, highly effective and low-risk surgical treatment options could be used. In Parkinson's Disease; findings such as chest wall rigidity and weakness of the respiratory muscle strength occur. The aim of this study was to determine the effect of preop and postop DBS surgery on respiratory muscle strength, respiratory function and physical performance in patients with Parkinson's disease.

Full description

In the study, at least 10 patients with Parkinson's disease who had DBS surgery in Mustafa Kemal University Research and Practice Hospital, Department of Brain and Nerve Surgery will be evaluated. Demographic-physical features, pulmonary functions, respiratory muscle strength, exercise capacity, functionality, and muscle strength will be evaluated

Enrollment

10 estimated patients

Sex

All

Ages

40 to 70 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Lack of any neurological disease other than Parkinson's
  • DBS surgery to be performed in the STN region

Exclusion criteria

  • Patients with advanced cognitive impairment
  • Patients with pulmonary, neurological and orthopedic diseases affecting functionalities
  • Pregnancy
  • Patients in whom the stimulation was canceled due to infection after surgery.

Trial design

Primary purpose

Supportive Care

Allocation

N/A

Interventional model

Single Group Assignment

Masking

None (Open label)

10 participants in 1 patient group

Parkinson's Disease Group
Experimental group
Description:
MIP and MEP Respiratory Function Test Strength Test
Treatment:
Device: MIP and MEP

Trial contacts and locations

1

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Central trial contact

Bircan Yucekaya, MSc; Deran Oskay, PhD

Data sourced from clinicaltrials.gov

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