The Effects of Dietary Fiber in CKD: A Systematic Review and Meta-analysis

Unity Health Toronto

Status: Completed

Conditions: Chronic Kidney Disease

Study type: Observational

Funder types: Other

Identifiers

NCT01844882

SMH-CKD-2013

Details and patient eligibility

About

Chronic kidney disease (CKD) is a debilitating condition in which there is a gradual decline of renal function associated with increased overall mortality. Most dietary guidelines for CKD focus on limiting protein intake (nitrogen) and high phosphorus-containing foods. However, increasing dietary fiber has been proposed to increase fecal nitrogen excretion which may ameliorate the progress of CKD. We therefore plan to conduct a systematic review and meta-analysis on clinical trials to assess the effect of fiber on urea and creatinine as classical markers of a state of uremia in individuals with CKD. We hypothesize that increasing fiber intakes will improve urea and creatinine levels in individuals with CKD.

Enrollment: 1 patient

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Dietary trials in humans
• Randomized treatment allocation
• Suitable control (low fiber)
• viable endpoint data

Exclusion criteria

• Non-human studies
• Nonrandomized treatment allocation
• Lack of a suitable control (high protein)
• no viable endpoint data

Trial design

1 participants in 1 patient group

Chronic Kidney Disease