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The Effects of Dietary Intake of Cod Residual Material Meal on Lipid Regulation, Glucose Regulation and Body Composition in Physically Active Adults (COD2016)

U

University of Bergen

Status

Completed

Conditions

Healthy
Physical Activity

Treatments

Dietary Supplement: Cod meal from residual material
Dietary Supplement: Control

Study type

Interventional

Funder types

Other

Identifiers

NCT03538834
2015/75 part 2

Details and patient eligibility

About

A high intake of fish is associated with positive health effects, including prevention and treatment of chronic non-communicable diseases, such as cardiovascular diseases (CVDs) and type 2 diabetes. These health effects have traditionally been attributed to the omega-3 fatty acids in fatty fish, but recent studies have suggested that also fish proteins may improve biomarkers of metabolic disease. Intake of cod fillet have previously shown beneficial effects on blood lipids, glucose regulation and body composition in adults with overweight or obesity. Health effect of cod residual material from fillet production (i.e., head, backbone, skin, cutoffs and entrails) have so far not been investigated, but residuals from other fish species have shown promising effects on glucose regulation in rats. The main aim of the current study is to investigate the effects of cod residual meal on serum lipids and glucose regulation in healthy, physically active adults.

Enrollment

70 estimated patients

Sex

All

Ages

20 to 55 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • BMI ≥ 18.5 kg/m2
  • Fasting blood glucose ≤7 mmol/L
  • Physically active
  • Percent body fat, 5-25 % for men and 12-35 % for women

Exclusion criteria

  • Allergies towards fish, milk, egg, gluten
  • Tobacco use > 10 cigarettes (or snus) per day
  • Diseases affecting the heart, intestinal function, kidney function or insulin secretion
  • Medications targeting cholesterol -or glucose metabolism, hypertension
  • Use of dietary supplements
  • Pregnancy or lactation

Trial design

Primary purpose

Basic Science

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Quadruple Blind

70 participants in 2 patient groups, including a placebo group

Cod meal from residual material
Experimental group
Description:
Dietary supplement: cod meal from residual material, 8 g protein daily for 8 weeks
Treatment:
Dietary Supplement: Cod meal from residual material
Control
Placebo Comparator group
Description:
Control group receive tablet containing fillers and no protein
Treatment:
Dietary Supplement: Control

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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