The Effects of Different Montages of tDCS on Muscle Strength in Healthy Adults

Mahidol University

Status: Completed

Conditions: Healthy

Treatments: Device: Transcranial direct current stimulation

Study type: Interventional

Funder types: Other

Identifiers

NCT04672109

MU2020

Details and patient eligibility

About

To investigate the effects of different montages of tDCS on muscle strength in healthy adults

Full description

Electrode montage or placement of tDCS over primary motor cortex can be categorized into unilateral (anodal or cathodal electrode over primary motor area) and bilateral tDCS (both anodal and cathodal electrode over the cortex). Previous studies reported benefits of different tDCS montages on muscle performance in healthy participants. However, there is no guideline for tDCS montages. This study aims to investigate immediate effects of different tDCS montages on muscle strength in healthy participants.

Enrollment: 80 patients

Sex: All

Ages: 18 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Healthy adults
2. Age range between 18 - 60 years old
3. Right-handed dominant identified by the Edinburg Handedness Inventory
4. No recent muscle injuries of both limbs for a past 6-months

Exclusion criteria

1. Consumed caffeine within 24 hours prior the experiment
2. History of neurological symptoms i.e. seizures, weakness, loss of sensation or unclear history of pass illness
3. Present of metal implantation, intracranial shunt, cochlear implantation or cardiac pacemakers
4. Present of opened wound or infectious wound around scalp

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Factorial Assignment

Masking: Triple Blind

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80 participants in 4 patient groups

Anodal-tDCS

Experimental group

Description:

Anodal transcranial direct current stimulation (tDCS) will be applied for 20 mins. Anode on the primary motor area (M1) of dominant hemisphere and Cathode on the supraorbital area of non-dominant hemisphere. Current intensity is fixed at 2 mA and current will flow continuously. The scope of intervention is to investigate effect of tDCS on muscle strength.

Treatment:

Device: Transcranial direct current stimulation

Cathodal-tDCS

Experimental group

Description:

Cathodal transcranial direct current stimulation (tDCS) will be applied for 20 mins. Cathode on the primary motor area (M1) of non-dominant hemisphere and Anode on the supraorbital area of dominant hemisphere. Current intensity is fixed at 2 mA and current will flow continuously. The scope of intervention is to investigate effect of tDCS on muscle strength.

Treatment:

Device: Transcranial direct current stimulation

Dual-tDCS

Experimental group

Description:

Dual transcranial direct current stimulation (tDCS) will be applied for 20 mins. Anode on the primary motor area (M1) of dominant hemisphere and Cathode on the primary motor area of non-dominant hemisphere. Current intensity is fixed at 2 mA and current will flow continuously. The scope of intervention is to investigate effect of tDCS on muscle strength.

Treatment:

Device: Transcranial direct current stimulation

Sham-tDCS

Sham Comparator group

Description:

Dual transcranial direct current stimulation (tDCS) will be applied over C3-C4 or the motor area (M1) for 20 mins. Anode on dominant hemisphere, Cathode on non-dominant hemisphere. The scope of intervention is to investigate effect of tDCS on muscle strength.

Treatment:

Device: Transcranial direct current stimulation